The JFK 50 Mile runs from Boonsboro to Williamsport as a single point-to-point course, crossing three distinct terrains: rocky mountain trail, flat towpath, then rolling country roads. You start at 6:30, from the Historic Boonsboro Inn.
The day's longest sustained climb comes right at the start, from Boonsboro up to the summit of Lambs Knoll, on the Appalachian Trail through South Mountain State Park. The rocky trail then drops back down through Crampton Gap before reaching Weverton, where the course leaves the Appalachian Trail.
From there, the long flat stretch of the C&O Canal Towpath begins, inside the C&O Canal National Historical Park along the Potomac River: dozens of nearly flat kilometers, past Antietam Creek around the midpoint, then a stretch by Ferry Hill.
The route leaves the towpath near Horseshoe Bend, crosses Downsville and picks up rolling country roads into the finish at Williamsport's Springfield Middle School — inside a 13-hour cutoff.
Paths and places: © OpenStreetMap contributors. Altitudes measured on the route.